Two Different Clinical Presentations of Acute Limb Ischemia Caused by Acute Thrombotic Events in COVID-19

9/12/2021 12:00:00 AM

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Authors: Yudistira Panji Santosa, Angelina Yuwono

Publication date: 12 September 2021

Cureus

Volume: 13 (9); e17916   

Link:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8511142/

 

Abstract

Coronavirus disease 2019 (COVID-19) is a global pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coagulopathy is frequently found in severe cases of COVID-19 and is usually manifested as a prothrombotic state. Hyperinflammation, endotheliitis, and immobilization during illness are hypothesized to play a role. Acute limb ischemia (ALI) is one of the presentations of arterial thrombosis in COVID-19. We present two cases of middle-aged men with COVID-19 infection, who developed ALI. The first patient developed ALI after 16 days from the initial COVID-19 diagnosis, and the second patient was admitted to the emergency ward due to sudden discoloration of his right lower limb, and COVID-19 was diagnosed during the evaluation.

 

Keywords: covid-19, thrombosis, acute limb ischemia, hypercoagulable state, arterial thrombosis