Meningocephalitis Caused by Epstein-Barr Virus In Adult With Lung Tuberculosis

2/8/2019 12:00:00 AM

---

Authors: Rr Josephine Retno Widayanti, Enty Tjoa, Yenna Tasia, Margareta Diyan Novina Jati, Aurelia Vania

Publication date: March 11, 2017

J Neurol Stroke

Volume: 6(3): 00202. DOI: 10.15406/jnsk.2017.06.00202.

Link: http://medcraveonline.com/JNSK/JNSK-06-00202.pdf

 

Abstract

Epstein-Barr virus (EBV) infections usually cause mild symptoms and resolves spontaneously, however the virus may cause severe complications such as neurological    diseases,    malignant    diseases    and    myocarditis.    Determining a diagnosis requires molecular, serological and imaging procedures. The therapeutic modalities  for  EBV-related severe organ damage including central nervous  system  manifestations  are  still  uncertain.  We  report  a  31-year-old man with lung tuberculosis with EBV meningoencephalitis presenting with prolonged  fever  and  altered  consciousness.  Cranial  imaging  was  consistent with  meningoencephalitis  characteristics.  The  diagnosis  was  made  by  EBV- DNA amplification in cerebrospinal fluid samples. In this case report, we aim to describe a meningoencephalitis caused by EBV in adult with underlying other organ infection